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MNC - Maximum Neighborhood Component


Definition

The neighborhood of a node v, nodes adjacent to v, induce a subnetwork N(v). The score of node v, MNC(v), is defined to be the size of the maximum connected component of N(v). The neighborhood N(v) is the set of nodes adjacent to v and does not contain node v.

MNC(v) = |V(MC(v))|

where MC(v) is a maximum connected component of the G[N(v)] and G[N(v)] is the induced subgraph of G by N(v).

References

  • CHEN, S.-H., CHIN, C.-H., WU, H.-H., HO, C.-W., KO, M.-T. & LIN, C.-Y. cyto-Hubba: A Cytoscape plug-in for hub object analysis in network biology. 20th International Conference on Genome Informatics, 2009.
  • LIN, C.-Y., CHIN, C.-H., WU, H.-H., CHEN, S.-H., HO, C.-W. & KO, M.-T. 2008. Hubba: hub objects analyzer—a framework of interactome hubs identification for network biology. Nucleic acids research, 36, W438-W443.


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